The ALS Association
ALS Ice Bucket Challenge Progress

Clinical Management Grant


Request For Proposals

Call Open for Abstract Submission March 15, 2017

Program Description
The aim of the ALS Association TREAT ALS™ Clinical Management Grant Program is to improve care and living with ALS with a focus on clinical, psychological and or social management of ALS.

BUDGET: A maximum of $100,000 per year for a maximum of 2 years.

Instructions for on-line submission.
Platform open for letter of intent April 22, 2017.

Step 1:
Register using this link:

Step 2:
Login using this link

Step 3:
Submit an abstract for an open call using the relevant link.

E-mail for queries.

Brief study outline: April 21, 2017
Request to submit full application: May 10, 2017
Submission of full application: June 6, 2017
Notification of award: September 1, 2017

Program Description
Examples of relevant clinical management studies for this mechanism include, but are not limited to, the following:

  • Studies that address the gaps in the delivery of care (as outlined in the ALS practice parameters)
  • Studies that explore and develop telemedicine for the care of individuals with ALS
  • Psychological interventions in ALS to address the significant mental health issues facing ALS patients and care givers
  • Nutritional and respiratory intervention
  • Studies to address the needs of care givers for patients with ALS and cognitive/behavioral impairment
  • Development of novel endpoints for clinical trial
  • Assistive Technology

Contract Information
This call supports research aimed at improving the lives of people living with ALS and their families. The proposed studies are expected to generate data that can be implemented in ALS clinical centres. Applicants must clearly and explicitly articulate what impact the project may have on the quality of life for people with ALS. Clinical trials will not be supported with this funding opportunity.


  • Maximum $100,000 per year for 2 years
  • The maximum allowable direct and indirect cost (maximum of 10% allowed) for the entire period of performance is $200,000

Review Criteria for letter of intent
Scientific Merit: Statistical design will be critically assessed and ability to enrol within the granting period will be critically evaluated.
Relevance to ALS: The impact that the study will have for people with ALS will be evaluated.
Originality of Research: The proposed study will be evaluated in context of current practice and how results may impact a change in practice to benefit people living with ALS and their families.

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