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YOU can make an impact: Neuro Collaborative

Thank you for your interest in funding the Neuro Collaborative, a unique partnership between three leading California researchers and their labs aimed at driving potential therapeutics for ALS quickly toward FDA approval.

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The Neuro Collaborative includes Clive Svendsen, Ph.D. at Cedars-Sinai in Los Angeles; Steven Finkbeiner, M.D., Ph.D. at Gladstone Institutes, affiliated with University of California San Francisco; and Don Cleveland, Ph.D. at University of California San Diego.

(left to right) Dr. Don Cleveland, Dr. Clive Svendsen and Dr. Steven Finkbeiner

The synergetic model brings together complementary expertise to advance understanding of ALS and drug development.

Each laboratory focuses on different areas of ALS research, including gene therapy, induced pluripotent stem cell (iPSC) models and drug screening to maximize shared knowledge and understanding of the complexities of the disease, while increasing industry interest and investment in ALS drug development.

The ALS Association was instrumental in the development of the Neuro Collaborative and announced funding for it within just a few months of the ALS Ice Bucket Challenge, contributing $5 million with the help from The ALS Association Orange County and Wisconsin Chapters.

Progress is already being made with the development of a SOD1 antisense drug that is currently being tested in a phase I/II clinical trial, and a similar trial focused on antisense technology targeting C9orf72, the most common genetic form of ALS, is expected in 2017 both through a partnership with Ionis Pharmaceuticals and Biogen.

Your support is urgently needed so please consider making a donation to support the Neuro Collaborative today. To learn more about this opportunity to give, please contact us.

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