A Comparison of early versus conventional initiation of non-invasive positive ventilation pressure ventilation (NPPV) in ALS
Carlayne Jackson, MD
University of Texas Health Science Center, San Antonio
Hypothesis:
The early detection of respiratory dysfunction intervention with NIV will improve QOL and prolong survival.
Aim:
Compare survival, QOL and success with NIV among patients who began NIV when initial nocturnal desaturation was documented (Group 1) and those who began NIV when FVC declined below 50% or when hypoventilation symptoms appear (Group #2)
Status:
The study is completed. More research is needed in this area. Presentations have been made and manuscripts published.
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