The ALS Association Research Program

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The Leader in Global ALS Research

The ALS Association has committed $99 million to find effective treatments and a cure for Lou Gehrig’s Disease. Our global research effort has helped increase the number of scientists working on ALS, advanced new discoveries and treatments, and has shed light on the complex genetic and environmental factors involved in ALS.  

The ALS Association has funded significant research milestones in the fight against ALS, including:

International Science Journal Profiles The ALS Association

In a recent interview in Nature, The ALS Association’s Chief Scientist, Lucie Bruijn, Ph.D. M.B.A., discussed how funds from the ALS Ice Bucket Challenge have expanded The Association’s research program and led to exciting new research opportunities, including potentially bringing novel treatment approaches to clinical trial within the next three years.

Dr. Bruijn also explained how The Association carries out its research missions by working with academic and industry partners and supporting researchers throughout the world at every level of their careers. She discussed how The Association’s programs have contributed to a better understanding of the genetics of the disease and facilitated several preclinical studies and trials.

Finally, Dr. Bruijn offered insight into The Association’s plans to invest in research studies that focus on five strategic areas: clinical research, biomarker discovery, genetics, drug development, and disease models.

Read the full interview with Dr. Bruijn and learn more about The ALS Association’s research program.

Project MinE

The ALS Association funds Project MinE to support sequencing of ALS genes

The ALS Association announced its financial commitment of $1 million to Project MinE. The funding will be used to bring this important effort to the United States, under the direction of researchers at University of Massachusetts Medical School in Worcester, Massachusetts, and Emory University in Atlanta, Georgia.

Funding for the project is made possible by the unprecedented outpouring of support from this summer’s Ice Bucket Challenge.

To understand the genetic basis of ALS and to ultimately find a cure for this devastating disease, Project MinE will map the DNA profiles of at least 15,000 ALS patients and 7,500 controls and perform comparative analyses on these 22,500 DNA profiles.

Learn more about The ALS Association's participation in Project MinE.

Meet our Project MinE researchers and ambassador.

Join the fight and help us discover the genetic basis of ALS. Start or support a local initiative to raise funds.

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Research ALS Today

The ALS Association's National Research Periodical provides in-depth coverage of current research projects and exciting clinical trials.

Resources for Researchers

Upcoming meetings, funding opportunities, and more.

Research Webinars and Videos

Monthly online webinars featuring leading ALS researchers, presenting various topics of ALS research and clinical trials.

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