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Clinical Trials

Note: This document is prepared as a service for the ALS community and is intended as general information. Content used in this report is obtained from informed members of the pharmaceutical industry and the ALS community.

For further information on drug trials, ClinicalTrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions. For an overview of clinical trials information, click here.

OPEN TRIALS

Compound or Trial Status & Sites Company or Center
Major Depression in ALS  Now Enrolling  University of South Carolina
AVP-923 in PBA Patients  Now Enrolling  Multi-center
Quality of Life Survey  Now Enrolling  Hershey ALS Clinic
Memantine Therapy  Now Enrolling  Banner Good Samaritan ALS clinic
Memantine Trial  Now Enrolling  University of Alberta
Trial for Familial ALS Now Enrolling   Emory University

New Gene Study

Enrollment Open  Massachusetts General Hospital

Ceftriaxone

Now Enrolling

Northeast ALS Consortium

 

 

RECENT NEWS IN CLINICAL TRIALS

July 11, 2006
Twenty Drugs Show Promise for ALS
June 12, 2006
Trial of Ceftriaxone Begins Enrolling ALS Patients

CLOSED TRIALS

Compound or Trial

 Status

Company or Center

Tamoxifen

Enrollment Closed

The University of Wisconsin-Madison

Thalidomide

Enrollment Closed

Dartmouth-Hitchcock Medical Center

Diaphragm Training Enrollment Closed Beth Israel Deaconess Medical Center
National Registry of Veterans with ALS  Enrollment Closed Durham, North Carolina VAMC

Combination Therapy
Selection Trial in ALS

Enrollment Closed Multicenter

Sodium Phenylbutyrate

Enrollment Closed Multicenter
The Vest  Enrollment Closed

Hill-Rom

Creatine Enrollment Closed The Carolinas Neuromuscular/ALS Center
Myotrophin® Enrollment Closed Cephalon
Celebrex Study Closed Northeast ALS Consortium
NEOTROFINTM  Study Closed  NeoTherapeutics, Inc.
NAALADase Study Closed Guilford Pharmaceuticals Inc.
Neurodex Study Complete Avanir Pharmaceuticals
Rilutek® FDA approved drug currently available Aventis S.A.
Oxandrolone Study Completed The Carolinas Neuromuscular/ALS MDA Center
Pilot CoQ10  Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
High Dose Coenzyme Q10 Enrollment Closed The Eleanor and Lou Gehrig MDA/ALS Research Center
Pilot CoQ10 with imaging  Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
Topiramate (Topamax)  Study Completed North Eastern ALS Consortium
Xaliproden Preliminary analysis released 9/5/00 Sanofi-Synthelabo Inc.
Indinavir Study Completed Beth Israel Medical Center
Creatine Study Completed North Eastern ALS Consortium
Creatine Study Completed The West Virginia University School of Medicine
Minocycline Investigation Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
Buspirone Investigation Study Completed Multicenter ALS





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