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Clinical Management Research: Funded Grants

The ALS Association announced the first clinical management research grant awardees in 1998. Since then, 21 research projects have been funded, 14 of which are completed.

Updated November 2009

Current Grants

A Randomized Crossover Study of standard NIPPV and low expiratory pressure NIPPV in ALS patients
External nutrition in ALS patients with Ventilatory Failure: minimizing the work of breathing
Standard of Practice vs Polysomnography-Directed Nocturnal Non-Invasive Positive Pressure Ventilation in Preserving Respiratory Function and Quality of Life in ALS
Optimizing NIPPV Use for Patients with ALS: Pennsylvania Consortium
Development of Evidence-Based Practice Guidelines for Caregivers of Individuals with ALS and Cognitive Impairment: Pilot Study of an Educational Approach

Completed Grants

Developing an ALS-Specific QOL Instrument for ALS
Factors Which Affect Quality of Life in Caregivers
Measuring Quality of Life in Patients with ALS: A Pilot Study
Impact of Enteral Nutritional Support on the Quality of Life
Personal Hope and the Family Milieu: Impact on Medical Decision-Making and Quality of Life
A Comparison of early versus conventional initiation of non-invasive positive ventilation pressure ventilation (NPPV) in ALS
Measurement and Treatment of Respiratory Impairment in Patients with Amyotrophic Lateral Sclerosis
Randomized Placebo-Controlled Crossover Trial with Delta 9-Tetrahydrocannabinol (THC) for the Treatment of Cramps in Amyotrophic Lateral Sclerosis (ALS)
A Randomized, Double-Blind Placebo-Controlled Study of Safety and Efficacy of Botulinum Toxin type B in Sialorrhea in ALS
Assessment of Nutritional Needs in Amyotrophic Lateral Sclerosis
Diaphragm Training (DT) in Amyotrophic Lateral Sclerosis
Effects of a Strengthening Program on Maximum Voluntary Isometric Contraction, Functional Abilities, Fatigue and Quality of Life in Patients with ALS
Modifying Nutritional Therapy in ALS Patients with Changes in Respiratory Status
Prospective Study of Rapid CT Cerebral Blood Flow Imaging in the Detection of Cognitive Impairment in Sporadic ALS



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